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Myeloid Cell Surface Antigen CD33 (CD33) Antibody
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Catalogue No: abx025513
Price:
US$326.25
(Size: 80 µl)
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Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Research Articles on Myeloid Cell Surface Antigen CD33 (CD33)
| Target | Myeloid Cell Surface Antigen CD33 (CD33) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 337-364 amino acids from human CD33. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Purified Mouse Monoclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20138 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E3P8, C9JEN7, F8WAL2, Q8TD24 |
| UniProt Entry Name | CD33_HUMAN |
| KEGG | hsa:945 |
| String | 9606.ENSP00000262262 |
| Molecular Weight | Calculated MW: 39.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |