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Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody
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Catalogue No: abx010523
Price:
US$420.50
(Size: 100 µl)
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CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
Research Articles on Hematopoietic Progenitor Cell Antigen CD34 (CD34)
| Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of CD34 expressed in E. Coli. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28906 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K664, Q15970, Q15971, Q5JTA3, Q5JTA4, Q9UJB1 |
| UniProt Entry Name | CD34_HUMAN |
| Gene Symbol | CD34 |
| GeneID | 947 |
| OMIM | 142230 |
| HGNC | 1662 |
| KEGG | hsa:947 |
| Ensembl | ENSG00000174059 |
| String | 9606.ENSP00000310036 |
| Molecular Weight | 41 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |