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T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G) Antibody
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Catalogue No: abx028446
Price:
US$290.00
(Size: 80 µl)
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CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, delta and zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.
Research Articles on T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G)
| Target | T-Cell Surface Glycoprotein CD3 Gamma Chain (CD3G) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human CD3G. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09693 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2HIZ6 |
| UniProt Entry Name | CD3G_HUMAN |
| NCBI Accession | NP_000064.1 |
| KEGG | hsa:917 |
| String | 9606.ENSP00000431445 |
| Molecular Weight | Calculated MW: 20.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |