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Target | Integrin Alpha IIb / CD41 Heavy Chain (ITGA2B) |
Clonality | Monoclonal |
Clone | M988 |
Reactivity | Human, Monkey |
Tested Applications | IHC, FCM |
Host | Mouse |
Recommended dilutions | Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Isotype | IgG1 |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A affinity chromatography. |
Storage | Store at 2-8°C. Do not freeze. |
UniProt Primary AC | P08514 (UniProt, ExPASy) |
Gene Symbol | ITGA2B |
GeneID | 3674 |
KEGG | hsa:3674 |
String | 9606.ENSP00000262407 |
Buffer | PBS solution with 15 mM sodium azide. |
Specificity | The antibody reacts with alpha (a) subunit of CD41 (heavy chain; 120 kDa). CD41 is mainly expressed on platelets and megakaryocytes. The antibody HIP8 blocks platelet aggregation and completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. HIP8 is useful in the morphological and physiological studies of platelets and megakaryocytes. |
Concentration | 1 mg/ml |
Availability | Shipped within 5-12 working days. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |