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Membrane Cofactor Protein (CD46) Antibody
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Catalogue No: abx001390
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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CD46 Antibody is a Rabbit Polyclonal antibody against CD46. CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, this protein may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 is found in a cluster on chromosome 1q32 with other proteins that are structural components of the complement system. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
Research Articles on Membrane Cofactor Protein (CD46)
| Target | Membrane Cofactor Protein (CD46) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CD46 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15529 (UniProt, ExPASy) |
| UniProt Entry Name | MCP_HUMAN |
| Gene Symbol | CD46 |
| GeneID | 4179 |
| NCBI Accession | NP_722548.1 |
| KEGG | hsa:4179 |
| String | 9606.ENSP00000313875 |
| Molecular Weight | Calculated MW: 36 kDa/39 kDa/40 kDa/41 kDa/42 kDa/43 kDa/44 kDa Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
