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CD59 Glycoprotein (CD59) Antibody
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Catalogue No: abx011952
Price:
US$420.50
(Size: 100 µl)
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This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.
Research Articles on CD59 Glycoprotein (CD59)
| Target | CD59 Glycoprotein (CD59) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/50 - 1/200, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P13987 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PR17 |
| Gene Symbol | CD59 |
| GeneID | 966 |
| OMIM | 107271 |
| HGNC | 1689 |
| Ensembl | ENSG00000085063 |
| Molecular Weight | 14.2 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |