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T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Antibody
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Catalogue No: abx001112
Price:
US$217.50
(Size: 20 µl)
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CD86 Antibody is a Rabbit Polyclonal antibody against CD86. This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
Research Articles on T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86)
| Target | T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25-133 of human CD86. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42081 (UniProt, ExPASy) |
| UniProt Entry Name | CD86_HUMAN |
| Gene Symbol | CD86 |
| GeneID | 942 |
| NCBI Accession | NP_787058.4 |
| KEGG | hsa:942 |
| String | 9606.ENSP00000332049 |
| Molecular Weight | Calculated MW: 38 kDa Observed MW: 60 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |