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Target | TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) |
Clonality | Monoclonal |
Clone | E504 |
Reactivity | Human |
Tested Applications | FCM |
Host | Mouse |
Recommended dilutions | FCM: 10 µl/100 µl of whole blood or 106 cells. Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | APC |
Excitation/Emission | 651/660 |
Laser Line | 647 |
Immunogen | HUT-78 Human T cell lymphoma cell line. |
Isotype | IgG1 |
Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
UniProt Primary AC | P25445 (UniProt, ExPASy) |
Gene Symbol | FAS |
GeneID | 355 |
KEGG | hsa:355 |
String | 9606.ENSP00000347979 |
Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
Specificity | The antibody reacts with CD95 (Fas/APO-1), a 46 kDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule. |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |