Cell Division Cycle Protein 23 (CDC23) Antibody

CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Target	Cell Division Cycle Protein 23 (CDC23)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 140-168 amino acids from the N-terminal region of human CDC23.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UJX2 (UniProt, ExPASy)
UniProt Secondary AC	A8K6E5, B4E3A2, B7WP05, D3DQB7, O75433, Q53FN2, Q9BS73
UniProt Entry Name	CDC23_HUMAN
String	9606.ENSP00000378350
Molecular Weight	Calculated MW: 68.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow CDC23.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cell Division Cycle Protein 23 (CDC23)

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