+44 (0) 1223 755950
+1 832 327 7413
Cell Division Cycle 25C (CDC25C) Antibody
REQUEST MORE INFO
Catalogue No: abx010324
Price:
US$427.75
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
A member of the MPI phosphatase family. Activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. Shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. At least four transcript variants for this gene exist. Three splice variant isoforms have been described.
Research Articles on Cell Division Cycle 25C (CDC25C)
| Target | Cell Division Cycle 25C (CDC25C) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CDC25C expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P30307 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQB8, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1 |
| UniProt Entry Name | MPIP3_HUMAN |
| Gene Symbol | CDC25C |
| GeneID | 995 |
| OMIM | 157680 |
| HGNC | 1727 |
| KEGG | hsa:995 |
| Ensembl | ENSG00000158402 |
| String | 9606.ENSP00000321656 |
| Enzyme Commission Number | EC 3.1.3.48 |
| Molecular Weight | 58 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |