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CDC42 Effector Protein 2 (CDC42EP2) Antibody
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Catalogue No: abx029309
Price:
US$326.25
(Size: 80 µl)
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CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
Research Articles on CDC42 Effector Protein 2 (CDC42EP2)
| Target | CDC42 Effector Protein 2 (CDC42EP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14613 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RD85, Q9UNS0 |
| UniProt Entry Name | BORG1_HUMAN |
| Gene Symbol | CDC42EP2 |
| KEGG | hsa:10435 |
| String | 9606.ENSP00000279249 |
| Molecular Weight | Calculated MW: 22.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |