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Cell Division Cycle 6 (CDC6) Antibody
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Catalogue No: abx032767
Price:
US$290.00
(Size: 80 µl)
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Human Cdc6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Research Articles on Cell Division Cycle 6 (CDC6)
| Target | Cell Division Cycle 6 (CDC6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human Cdc6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99741 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8TB30 |
| UniProt Entry Name | CDC6_HUMAN |
| KEGG | hsa:990 |
| String | 9606.ENSP00000209728 |
| Molecular Weight | Calculated MW: 62.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |