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Parafibromin (CDC73) Antibody
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Catalogue No: abx000790
Price:
US$203.00
(Size: 20 µl)
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CDC73 Antibody is a Rabbit Polyclonal antibody against CDC73. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].
Research Articles on Parafibromin (CDC73)
| Target | Parafibromin (CDC73) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 435-505 of human HRPT2 / CDC73. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6P1J9 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NLZ8, B2RBR2, Q6PK51, Q96A07, Q9H245, Q9H5L7 |
| UniProt Entry Name | CDC73_HUMAN |
| Gene Symbol | CDC73 |
| GeneID | 79577 |
| KEGG | hsa:79577 |
| String | 9606.ENSP00000356405 |
| Molecular Weight | Calculated MW: 61 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |