Cadherin 10 (CDH10) Antibody

CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Target	Cadherin 10 (CDH10)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human CDH10.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y6N8 (UniProt, ExPASy)
UniProt Secondary AC	Q9ULB3
UniProt Entry Name	CAD10_HUMAN
Gene Symbol	CDH10
String	9606.ENSP00000264463
Molecular Weight	Calculated MW: 88.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Chicken CDH10.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cadherin 10 (CDH10)

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