Cadherin-13 (CDH13) Antibody

CDH13 Antibody is a Rabbit Polyclonal antibody against CDH13. This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011].

Target	Cadherin-13 (CDH13)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 120-370 of human Cadherin-13 (CDH13).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55290 (UniProt, ExPASy)
UniProt Secondary AC	A8W476, A8W477, B7Z590, C9JRI6, J3KN62, Q6GTW4, Q8TBX3
UniProt Entry Name	CAD13_HUMAN
Gene Symbol	CDH13
GeneID	1012
OMIM	601364
NCBI Accession	NP_001248.1
HGNC	1753
KEGG	hsa:1012
String	9606.ENSP00000268613
Molecular Weight	Calculated MW: 78 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cadherin-13 (CDH13)

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