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Cadherin 5 (CDH5) Antibody
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Catalogue No: abx000842
Price:
US$203.00
(Size: 20 µl)
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CDH5 Antibody is a Rabbit Polyclonal antibody against CDH5. This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Research Articles on Cadherin 5 (CDH5)
| Target | Cadherin 5 (CDH5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 259-358 of human VE Cadherin. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P33151 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4VAI5, Q4VAI6 |
| UniProt Entry Name | CADH5_HUMAN |
| Gene Symbol | CDH5 |
| GeneID | 1003 |
| NCBI Accession | NP_001786.2 |
| KEGG | hsa:1003 |
| String | 9606.ENSP00000344115 |
| Molecular Weight | Calculated MW: 88 kDa Observed MW: 130 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |