Cyclin-Dependent Kinase 1 (CDK1) Antibody

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

Target	Cyclin-Dependent Kinase 1 (CDK1)
Clonality	Monoclonal
Reactivity	Human, Mouse, Rat, Monkey
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CDK1 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P06493 (UniProt, ExPASy)
UniProt Secondary AC	A8K7C4, C9J497, O60764
UniProt Entry Name	CDK1_HUMAN
GeneID	983
KEGG	hsa:983
String	9606.ENSP00000378699
Enzyme Commission Number	EC 2.7.11.22 EC 2.7.11.23
Molecular Weight	34 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin-Dependent Kinase 1 (CDK1)

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