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Cyclin Dependent Kinase 1 Phospho-Ser39 (CDK1 pS39) Antibody
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Catalogue No: abx031848
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Research Articles on Cyclin Dependent Kinase 1 Phospho-Ser39 (CDK1 pS39)
| Target | Cyclin Dependent Kinase 1 Phospho-Ser39 (CDK1 pS39) |
| Clonality | Polyclonal |
| Target Modification | Ser39 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, DB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S39 of human CDK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06493 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C4, C9J497, O60764 |
| UniProt Entry Name | CDK1_HUMAN |
| KEGG | hsa:983 |
| String | 9606.ENSP00000378699 |
| Molecular Weight | Calculated MW: 34.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Chicken CDK1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |