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Cyclin Dependent Kinase 1 Phospho-Thr161 (CDK1 pT161) Antibody
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Catalogue No: abx000372
Price:
US$232.00
(Size: 20 µl)
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CDK1 (pT161) Antibody is a Rabbit Polyclonal antibody against CDK1 (pT161). The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Cyclin Dependent Kinase 1 Phospho-Thr161 (CDK1 pT161)
| Target | Cyclin Dependent Kinase 1 Phospho-Thr161 (CDK1 pT161) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around T161 of human CDK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06493 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C4, C9J497, O60764 |
| UniProt Entry Name | CDK1_HUMAN |
| Gene Symbol | CDK1 |
| GeneID | 983 |
| NCBI Accession | NP_001777.1 |
| KEGG | hsa:983 |
| String | 9606.ENSP00000378699 |
| Molecular Weight | Calculated MW: 34 kDa Observed MW: 34 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 0.418 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |