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Cyclin-Dependent Kinase 2 (CDK2) Antibody
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Catalogue No: abx033450
Price:
US$290.00
(Size: 80 µl)
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CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.
Research Articles on Cyclin-Dependent Kinase 2 (CDK2)
| Target | Cyclin-Dependent Kinase 2 (CDK2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CDK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P24941 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C6, O75100 |
| UniProt Entry Name | CDK2_HUMAN |
| KEGG | hsa:1017 |
| String | 9606.ENSP00000266970 |
| Molecular Weight | Calculated MW: 33.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Hamster and Xenopus CDK2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |