Cyclin-Dependent Kinase 2 (CDK2) Antibody

CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

Target	Cyclin-Dependent Kinase 2 (CDK2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from human CDK2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P24941 (UniProt, ExPASy)
UniProt Secondary AC	A8K7C6, O75100
UniProt Entry Name	CDK2_HUMAN
NCBI Accession	NP_001789.2 NP_439892.2
KEGG	hsa:1017
String	9606.ENSP00000266970
Molecular Weight	Calculated MW: 33.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Hamster and Xenopus CDK2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin-Dependent Kinase 2 (CDK2)

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