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CDK2 (pT14) Antibody
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Catalogue No: abx032049
Price:
US$326.25
(Size: 80 µl)
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CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.
Research Articles on CDK2 (pT14)
| Target | CDK2 (pT14) |
| Clonality | Polyclonal |
| Target Modification | Thr14 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T14 of human CDK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P24941 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C6, O75100 |
| UniProt Entry Name | CDK2_HUMAN |
| KEGG | hsa:1017 |
| String | 9606.ENSP00000266970 |
| Molecular Weight | Calculated MW: 33.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Hamster and Xenopus CDK2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |