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CDK2 (pT160) Antibody
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Catalogue No: abx000373
Price:
US$232.00
(Size: 20 µl)
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CDK2 (pT160) Antibody is a Rabbit Polyclonal antibody against CDK2 (pT160). The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.
Research Articles on CDK2 (pT160)
| Target | CDK2 (pT160) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around T160 of human CDK2 (NP_001789.2?/NP_001249.1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P24941 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C6, O75100 |
| UniProt Entry Name | CDK2_HUMAN |
| Gene Symbol | CDK2 |
| GeneID | 1017 |
| NCBI Accession | NP_001789.2 NP_001249.1 |
| KEGG | hsa:1017 |
| String | 9606.ENSP00000266970 |
| Molecular Weight | Calculated MW: 34 kDa Observed MW: 32 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |