+44 (0) 1223 755950
+1 832 327 7413
Cyclin-Dependent Kinase 9 (CDK9) Antibody
REQUEST MORE INFO
Catalogue No: abx011759
Price:
US$420.50
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Research Articles on Cyclin-Dependent Kinase 9 (CDK9)
| Target | Cyclin-Dependent Kinase 9 (CDK9) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CDK9 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P50750 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5JU24, Q5JU25, Q5U006, Q96TF1 |
| UniProt Entry Name | CDK9_HUMAN |
| Gene Symbol | CDK9 |
| GeneID | 1025 |
| OMIM | 603251 |
| HGNC | 1780 |
| KEGG | hsa:1025 |
| Ensembl | ENSG00000136807 |
| String | 9606.ENSP00000362361 |
| Enzyme Commission Number | EC 2.7.11.22 EC 2.7.11.23 |
| Molecular Weight | 43 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |