Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Target	Cyclin Dependent Kinase Inhibitor 1B (CDKN1B)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CDKN1B expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P46527 (UniProt, ExPASy)
UniProt Secondary AC	Q16307, Q5U0H2, Q9BUS6
UniProt Entry Name	CDN1B_HUMAN
Gene Symbol	CDKN1B
GeneID	1027
OMIM	600778
HGNC	1785
KEGG	hsa:1027
Ensembl	ENSG00000111276
String	9606.ENSP00000228872
Molecular Weight	22 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin Dependent Kinase Inhibitor 1B (CDKN1B)

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