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Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) Antibody
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Catalogue No: abx011962
Price:
US$427.75
(Size: 100 µl)
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This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Research Articles on Cyclin Dependent Kinase Inhibitor 1B (CDKN1B)
| Target | Cyclin Dependent Kinase Inhibitor 1B (CDKN1B) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CDKN1B expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P46527 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16307, Q5U0H2, Q9BUS6 |
| UniProt Entry Name | CDN1B_HUMAN |
| Gene Symbol | CDKN1B |
| GeneID | 1027 |
| OMIM | 600778 |
| HGNC | 1785 |
| KEGG | hsa:1027 |
| Ensembl | ENSG00000111276 |
| String | 9606.ENSP00000228872 |
| Molecular Weight | 22 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |