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Cyclin Dependent Kinase 4 Inhibitor C (CDKN2C) Antibody
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Catalogue No: abx001659
Price:
US$203.00
(Size: 20 µl)
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CDKN2C Antibody is a Rabbit Polyclonal antibody against CDKN2C. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Research Articles on Cyclin Dependent Kinase 4 Inhibitor C (CDKN2C)
| Target | Cyclin Dependent Kinase 4 Inhibitor C (CDKN2C) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-168 of human CDKN2C/p18-INK4C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42773 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8TB83 |
| UniProt Entry Name | CDN2C_HUMAN |
| Gene Symbol | CDKN2C |
| GeneID | 1031 |
| NCBI Accession | NP_523240.1 |
| KEGG | hsa:1031 |
| String | 9606.ENSP00000262662 |
| Molecular Weight | Calculated MW: 18 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |