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Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody
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Catalogue No: abx005030
Price:
US$203.00
(Size: 20 µl)
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CDKN2D Antibody is a Rabbit Polyclonal antibody against CDKN2D. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
Research Articles on Cyclin Dependent Kinase Inhibitor 2D (CDKN2D)
| Target | Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CDKN2D. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P55273 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13102, Q6FGE9 |
| UniProt Entry Name | CDN2D_HUMAN |
| Gene Symbol | CDKN2D |
| GeneID | 1032 |
| NCBI Accession | NP_001791.1 |
| KEGG | hsa:1032 |
| String | 9606.ENSP00000377224 |
| Molecular Weight | Calculated MW: 18 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |