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CDX2 (pS283) Antibody
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Catalogue No: abx032079
Price:
US$326.25
(Size: 80 µl)
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The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
Research Articles on CDX2 (pS283)
| Target | CDX2 (pS283) |
| Clonality | Polyclonal |
| Target Modification | Ser283 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC, DB |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/10 - 1/50, DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S283 of human CDX2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99626 (UniProt, ExPASy) |
| UniProt Secondary AC | O00503, Q5VTU7, Q969L8, Q9UD92 |
| UniProt Entry Name | CDX2_HUMAN |
| KEGG | hsa:1045 |
| String | 9606.ENSP00000370408 |
| Molecular Weight | Calculated MW: 33.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |