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Carcinoembryonic Antigen Related Cell Adhesion Molecule 7 (CEACAM7) Antibody
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Catalogue No: abx029319
Price:
US$326.25
(Size: 80 µl)
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CEA-related cell adhesion molecule 7 (CEACAM7, CGM2) belongs to the carcinoembryonic antigen (CEA) family. It encodes a glycosyl phosphatidyl inositol (GPI) linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constantlike A domain.
Research Articles on Carcinoembryonic Antigen Related Cell Adhesion Molecule 7 (CEACAM7)
| Target | Carcinoembryonic Antigen Related Cell Adhesion Molecule 7 (CEACAM7) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 112-140 amino acids from the Central region of human CEACAM7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14002 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K848, O15148, O15149, Q0VAC1, Q13983, Q9UPJ2 |
| UniProt Entry Name | CEAM7_HUMAN |
| KEGG | hsa:1087 |
| String | 9606.ENSP00000006724 |
| Molecular Weight | Calculated MW: 29.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |