CCAAT/Enhancer Binding Protein Alpha (CEBPA) Antibody

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP beta and CEBP gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Target	CCAAT/Enhancer Binding Protein Alpha (CEBPA)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CEBPA expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49715 (UniProt, ExPASy)
UniProt Secondary AC	A7LNP2, P78319, Q05CA4
UniProt Entry Name	CEBPA_HUMAN
Gene Symbol	CEBPA
GeneID	1050
OMIM	116897
HGNC	1833
KEGG	hsa:1050
Ensembl	ENSG00000245848
String	9606.ENSP00000427514
Molecular Weight	42 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CCAAT/Enhancer Binding Protein Alpha (CEBPA)

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