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CCAAT/Enhancer Binding Protein Alpha (CEBPA) Antibody
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Catalogue No: abx011898
Price:
US$427.75
(Size: 100 µl)
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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP beta and CEBP gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Research Articles on CCAAT/Enhancer Binding Protein Alpha (CEBPA)
| Target | CCAAT/Enhancer Binding Protein Alpha (CEBPA) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CEBPA expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49715 (UniProt, ExPASy) |
| UniProt Secondary AC | A7LNP2, P78319, Q05CA4 |
| UniProt Entry Name | CEBPA_HUMAN |
| Gene Symbol | CEBPA |
| GeneID | 1050 |
| OMIM | 116897 |
| HGNC | 1833 |
| KEGG | hsa:1050 |
| Ensembl | ENSG00000245848 |
| String | 9606.ENSP00000427514 |
| Molecular Weight | 42 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |