Chymotrypsin Like Elastase Family Member 1 (CELA1) Antibody

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.

Target	Chymotrypsin Like Elastase Family Member 1 (CELA1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CELA1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UNI1 (UniProt, ExPASy)
UniProt Secondary AC	Q5MLF0, Q6DJT0, Q6ISM6
UniProt Entry Name	CELA1_HUMAN
Gene Symbol	CELA1
GeneID	1990
OMIM	130120
HGNC	3308
KEGG	hsa:1990
Ensembl	ENSG00000139610
String	9606.ENSP00000293636
Molecular Weight	Calculated MW: 27.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chymotrypsin Like Elastase Family Member 1 (CELA1)

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