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Chymotrypsin Like Elastase Family Member 3A (CELA3A) Antibody
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Catalogue No: abx028089
Price:
US$290.00
(Size: 80 µl)
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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
Research Articles on Chymotrypsin Like Elastase Family Member 3A (CELA3A)
| Target | Chymotrypsin Like Elastase Family Member 3A (CELA3A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 157-186 amino acids from the Central region of human CELA3A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09093 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AQ53, Q9BRW4 |
| UniProt Entry Name | CEL3A_HUMAN |
| KEGG | hsa:10136 |
| String | 9606.ENSP00000290122 |
| Molecular Weight | Calculated MW: 29.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |