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Centromere Protein A (CENPA) Antibody
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Catalogue No: abx027638
Price:
US$290.00
(Size: 80 µl)
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Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4) 2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Research Articles on Centromere Protein A (CENPA)
| Target | Centromere Protein A (CENPA) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 82-110 amino acids from the Central region of human CENPA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49450 (UniProt, ExPASy) |
| UniProt Secondary AC | D6W544, Q53T74, Q9BVW2 |
| UniProt Entry Name | CENPA_HUMAN |
| KEGG | hsa:1058 |
| String | 9606.ENSP00000336868 |
| Molecular Weight | Calculated MW: 16 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Hamster CENPA. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |