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CFL1 (pS3) Antibody
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Catalogue No: abx000230
Price:
US$232.00
(Size: 20 µl)
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CFL1 (pS3) Antibody is a Rabbit Polyclonal antibody against CFL1 (pS3). The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Research Articles on CFL1 (pS3)
| Target | CFL1 (pS3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around S3 of human CFL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23528 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KUQ1, Q53Y87, Q9UCA2 |
| UniProt Entry Name | COF1_HUMAN |
| Gene Symbol | CFL1 |
| GeneID | 1072 |
| NCBI Accession | NP_005498.1 |
| KEGG | hsa:1072 |
| String | 9606.ENSP00000432660 |
| Molecular Weight | Calculated MW: 19 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |