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CASP8 And FADD Like Apoptosis Regulator (CFLAR) Antibody
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Catalogue No: abx015815
Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8.However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8.Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Research Articles on CASP8 And FADD Like Apoptosis Regulator (CFLAR)
| Target | CASP8 And FADD Like Apoptosis Regulator (CFLAR) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15519 (UniProt, ExPASy) |
| UniProt Entry Name | CFLAR_HUMAN |
| Gene Symbol | CFLAR |
| GeneID | 8837 |
| OMIM | 603599 |
| HGNC | 1876 |
| KEGG | hsa:8837 |
| Ensembl | ENSG00000003402 |
| String | 9606.ENSP00000312455 |
| Molecular Weight | 55.3 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |