+44 (0) 1223 755950
+1 832 327 7413
Properdin (CFP) Antibody
REQUEST MORE INFO
Catalogue No: abx034581
Price:
US$290.00
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3 and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
Research Articles on Properdin (CFP)
| Target | Properdin (CFP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 197-223 amino acids from the Central region of human CFP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P27918 (UniProt, ExPASy) |
| UniProt Secondary AC | O15134, O15135, O15136, O75826 |
| UniProt Entry Name | PROP_HUMAN |
| Gene Symbol | CFP |
| KEGG | hsa:5199 |
| String | 9606.ENSP00000247153 |
| Molecular Weight | Calculated MW: 51.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |