Chromatin Assembly Factor 1, Subunit B (CHAF1B) Antibody

CHAF1B Antibody is a Rabbit Polyclonal antibody against CHAF1B. Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.

Target	Chromatin Assembly Factor 1, Subunit B (CHAF1B)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human p60 CAF1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13112 (UniProt, ExPASy)
UniProt Secondary AC	Q99548
UniProt Entry Name	CAF1B_HUMAN
Gene Symbol	CHAF1B
GeneID	8208
NCBI Accession	NP_005432.1
KEGG	hsa:8208
String	9606.ENSP00000315700
Molecular Weight	Calculated MW: 61 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chromatin Assembly Factor 1, Subunit B (CHAF1B)

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