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Charged Multivesicular Body Protein 2b (CHMP2B) Antibody
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Catalogue No: abx027327
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Research Articles on Charged Multivesicular Body Protein 2b (CHMP2B)
| Target | Charged Multivesicular Body Protein 2b (CHMP2B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UQN3 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DJG8, Q53HC7, Q9Y4U6 |
| UniProt Entry Name | CHM2B_HUMAN |
| Gene Symbol | CHMP2B |
| String | 9606.ENSP00000263780 |
| Molecular Weight | Calculated MW: 23.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow CHMP2B. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |