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Charged Multivesicular Body Protein 2b (CHMP2B) Antibody
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Catalogue No: abx004134
Price:
US$203.00
(Size: 20 µl)
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CHMP2B Antibody is a Rabbit Polyclonal antibody against CHMP2B. This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Research Articles on Charged Multivesicular Body Protein 2b (CHMP2B)
| Target | Charged Multivesicular Body Protein 2b (CHMP2B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UQN3 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DJG8, Q53HC7, Q9Y4U6 |
| UniProt Entry Name | CHM2B_HUMAN |
| Gene Symbol | CHMP2B |
| GeneID | 25978 |
| NCBI Accession | NP_054762.2 |
| String | 9606.ENSP00000263780 |
| Molecular Weight | Calculated MW: 24 kDa Observed MW: 28 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |