Cholinergic Receptor, Nicotinic, Epsilon (CHRNE) Antibody

Cholinergic Receptor, Nicotinic, Epsilon (CHRNE) Antibody is a Rabbit Polyclonal antibody for the detection of CHRNE.

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Target	Cholinergic Receptor, Nicotinic, Epsilon (CHRNE)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Acetylcholine receptor subunit epsilon
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q04844 (UniProt, ExPASy)
UniProt Secondary AC	D3DTK6
UniProt Entry Name	ACHE_HUMAN
Gene Symbol	CHRNE
GeneID	1145
KEGG	hsa:1145
String	9606.ENSP00000293780
Molecular Weight	Observed MW: 45 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Cholinergic Receptor, Nicotinic, Epsilon (CHRNE)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue