Chondroitin Sulfate Proteoglycan 4 (CSPG4) Antibody

Chondroitin Sulfate Proteoglycan 4 (CSPG4) Antibody is a Rabbit Polyclonal antibody for the detection of CSPG4.

CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2 (VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.

Target	Chondroitin Sulfate Proteoglycan 4 (CSPG4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	chondroitin sulfate proteoglycan 4
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q6UVK1 (UniProt, ExPASy)
UniProt Secondary AC	D3DW77, Q92675
UniProt Entry Name	CSPG4_HUMAN
Gene Symbol	CSPG4
GeneID	1464
OMIM	601172
HGNC	2466
KEGG	hsa:1464
Ensembl	ENSG00000173546
String	9606.ENSP00000312506
Molecular Weight	Observed MW: 270 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Chondroitin Sulfate Proteoglycan 4 (CSPG4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue