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Muscarinic Acetylcholine Receptor M2 (CHRM2) Antibody
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Catalogue No: abx028043
Price:
US$326.25
(Size: 80 µl)
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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Research Articles on Muscarinic Acetylcholine Receptor M2 (CHRM2)
| Target | Muscarinic Acetylcholine Receptor M2 (CHRM2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 336-364 amino acids from the Central region of human CHRM2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P08172 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4VBK6, Q9P1X9 |
| UniProt Entry Name | ACM2_HUMAN |
| KEGG | hsa:1129 |
| String | 9606.ENSP00000399745 |
| Molecular Weight | Calculated MW: 51.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig CHRM2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |