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Cholinergic Receptor, Nicotinic Alpha 10 (CHRNA10) Antibody
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Catalogue No: abx026642
Price:
US$326.25
(Size: 80 µl)
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CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
Research Articles on Cholinergic Receptor, Nicotinic Alpha 10 (CHRNA10)
| Target | Cholinergic Receptor, Nicotinic Alpha 10 (CHRNA10) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9GZZ6 (UniProt, ExPASy) |
| UniProt Entry Name | ACH10_HUMAN |
| Gene Symbol | CHRNA10 |
| String | 9606.ENSP00000250699 |
| Molecular Weight | Calculated MW: 49.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat CHRNA10. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |