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Cholinergic Receptor, Nicotinic Alpha 3 (CHRNA3) Antibody
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Catalogue No: abx032382
Price:
US$326.25
(Size: 80 µl)
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CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Research Articles on Cholinergic Receptor, Nicotinic Alpha 3 (CHRNA3)
| Target | Cholinergic Receptor, Nicotinic Alpha 3 (CHRNA3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P32297 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15823, Q4KMN8, Q86U77, Q96RH3, Q99553, Q9BQ93, Q9BRR4 |
| UniProt Entry Name | ACHA3_HUMAN |
| Gene Symbol | CHRNA3 |
| KEGG | hsa:1136 |
| String | 9606.ENSP00000315602 |
| Molecular Weight | Calculated MW: 57.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow CHRNA3. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |