Chromobox Protein Homolog 1 (CBX1) Antibody

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family.The protein is enriched in the heterochromatin and associated with centromeres.The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins.The protein may play an important role in the epigenetic control of chromatin structure and gene expression.Several related pseudogenes are located on chromosomes 1, 3, and X.Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target	Chromobox Protein Homolog 1 (CBX1)
Clonality	Monoclonal
Reactivity	Human, Monkey
Tested Applications	ELISA, WB, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CBX1 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	21 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chromobox Protein Homolog 1 (CBX1)

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