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Chromobox Protein Homolog 8 (CBX8) Antibody
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Catalogue No: abx015789
Price:
US$427.75
(Size: 100 µl)
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Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis.CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.
Research Articles on Chromobox Protein Homolog 8 (CBX8)
| Target | Chromobox Protein Homolog 8 (CBX8) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9HC52 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96H39, Q9NR07 |
| UniProt Entry Name | CBX8_HUMAN |
| Gene Symbol | CBX8 |
| GeneID | 57332 |
| OMIM | 617354 |
| HGNC | 15962 |
| Ensembl | ENSG00000141570 |
| String | 9606.ENSP00000269385 |
| Molecular Weight | 43.4 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |