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Cell Death Activator CIDE-A (CIDEA) Antibody
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Catalogue No: abx027772
Price:
US$326.25
(Size: 80 µl)
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This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Research Articles on Cell Death Activator CIDE-A (CIDEA)
| Target | Cell Death Activator CIDE-A (CIDEA) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60543 (UniProt, ExPASy) |
| UniProt Secondary AC | B0YIY7, Q6UPR7 |
| UniProt Entry Name | CIDEA_HUMAN |
| Gene Symbol | CIDEA |
| KEGG | hsa:1149 |
| String | 9606.ENSP00000320209 |
| Molecular Weight | Calculated MW: 24.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |