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Keratin, Type II Cytoskeletal 7 (KRT7) Antibody
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Catalogue No: abx010567
Price:
US$420.50
(Size: 100 µl)
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CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Research Articles on Keratin, Type II Cytoskeletal 7 (KRT7)
| Target | Keratin, Type II Cytoskeletal 7 (KRT7) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CK7 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P08729 (UniProt, ExPASy) |
| UniProt Secondary AC | Q92676, Q9BUD8, Q9Y3R7 |
| UniProt Entry Name | K2C7_HUMAN |
| Gene Symbol | KRT7 |
| GeneID | 3855 |
| OMIM | 148059 |
| HGNC | 6445 |
| KEGG | hsa:3855 |
| Ensembl | ENSG00000135480 |
| String | 9606.ENSP00000329243 |
| Molecular Weight | 51 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |