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Claudin 1 (CLDN1) Antibody
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Catalogue No: abx010569
Price:
US$348.00
(Size: 50 µl)
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Claudin 1 antibody detects endogenous levels of total Claudin 1. claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.
Research Articles on Claudin 1 (CLDN1)
| Target | Claudin 1 (CLDN1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/3000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthesised peptide derived from human Claudin 1 |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95832 (UniProt, ExPASy) |
| UniProt Entry Name | CLD1_HUMAN |
| Gene Symbol | CLDN1 |
| KEGG | hsa:9076 |
| Ensembl | ENSG00000163347 |
| String | 9606.ENSP00000295522 |
| Molecular Weight | 22 kDa |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Specificity | Claudin 1 antibody detects endogenous levels of total Claudin 1 |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |