H(+)/Cl(-) Exchange Transporter 4 (CLC4) Antibody

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders.

Target	H(+)/Cl(-) Exchange Transporter 4 (CLC4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 663-689 amino acids from the C-terminal region of human CLC4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51793 (UniProt, ExPASy)
UniProt Secondary AC	A1L3U1, B7Z5Z4, Q9UBU1
UniProt Entry Name	CLCN4_HUMAN
KEGG	hsa:1183
String	9606.ENSP00000370213
Molecular Weight	Calculated MW: 84.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat CLCN4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on H(+)/Cl(-) Exchange Transporter 4 (CLC4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue